1-Pentyl-3-1-naphthoylindole

1-Pentyl-3-(1-naphthoyl) indole

SIZE GLOBAL PURCHASING
1 mg, 5 g, 10 g, 100g , 500g, 1kg
Purity: 99.8
Appearance: white powder
grade analytical standard
Specification: 99% HPLC
Molecular Formula: C9H9NO
Molecular weight: 147.17
assay ≥98.0% (HPLC)
form neat
drug control USDEA Schedule I; regulated under CDSA

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Description

1-Pentyl-3-(1-naphthoyl) indole

 

1-Pentyl-3-1-naphthoylindole SIZE GLOBAL PURCHASING
1 mg, 5 g, 10 g, 100g , 500g, 1kg
Purity: 99.8
Appearance: white powder
grade analytical standard
Specification: 99% HPLC
Molecular Formula: C9H9NO
Molecular weight: 147.17
assay ≥98.0% (HPLC)
form neat
drug control USDEA Schedule I; regulated under CDSA

1-Pentyl-3-1-naphthoylindole

indole

Indole a new class of cannabimimetic , with 3-phenylacetyl or substituted 3-phenylacetyl substituents, has been prepared and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. In general those compounds with a 2-substituted phenylacetyl group have good affinity for both receptors. The 4-substituted analogs have little affinity for either receptor, while the 3-substituted compounds are intermediate in their affinities. Two of these compounds, 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251) and 1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH-302), have 5-fold selectivity for the CB1 receptor with modest affinity for the CB2 receptor. GTPγS determinations indicate that both compounds are highly efficacious agonists at the CB1 receptor and partial agonists at the CB2 receptor. 1-Pentyl-3-1-naphthoylindole

 

It’s need.Indole a new class of cannabimimetic , with 3-phenylacetyl or substituted 3-phenylacetyl substituents, has been prepared and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. In general those compounds with a 2-substituted phenylacetyl group have good affinity for both receptors. The 4-substituted analogs have little affinity for either receptor, while the 3-substituted compounds are intermediate in their affinities. Two of these compounds, 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251) and 1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH-302), have 5-fold selectivity for the CB1 receptor with modest affinity for the CB2 receptor. GTPγS determinations indicate that both compounds are highly efficacious agonists at the CB1 receptor and partial agonists at the CB2 receptor. 1-Pentyl-3-1-naphthoylindole

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